Spitz nevi and other Spitzoid lesions: Part II. Natural History and Management
Identifieur interne : 004B31 ( Main/Exploration ); précédent : 004B30; suivant : 004B32Spitz nevi and other Spitzoid lesions: Part II. Natural History and Management
Auteurs : Su Luo [États-Unis] ; Alireza Sepehr [États-Unis] ; Hensin Tsao [États-Unis]Source :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 2011.
Abstract
(In Part II of this CME, we will maintain the terminology defined in Part I for purposes of continuity. Again, “Spitz tumor” is used as the umbrella term for the entire, category of lesions; common Spitz Nevi (CSN) refers to only the most typical lesions seen in pediatric cases; and atypical Spitz tumors (ASTs) encompasses the “all other” category which continues to cause debate.)
For dermatologists, evidence-based management guidelines for Spitz tumors have not been established. Despite the lack of a standardized approach, most dermatologists recommend excision of Spitz tumors occurring in adults, and adopt more conservative measures towards pediatric cases. The histopathological attributes and the clinical scenario are factored into management in each case. While the metastatic behavior of certain Spitz tumors is well-known, the malignant potential of these lesions remains unclear as they only rarely result in negative outcomes. The risks and benefits of adjunctive measures, such as sentinel lymph node biopsy and interferon use, remain untested, and subjects of ongoing controversy.
Url:
DOI: 10.1016/j.jaad.2011.06.045
PubMed: 22082839
PubMed Central: 3217195
Affiliations:
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